PEOPLE
Dr. Helge Feddersen
Postdoctoral Researcher
Research topics & projects
Bacillus subtilis, Min system, Single-molecule localization microscopy, Singe-particle tracking, Genetic engineering- and biosafety
Education & positions
since 2022 Biosafety officer of Christian-Albrechts-University Kiel
since 2020 Postdoctoral researcher, Christian-Albrechts-University Kiel
2015 - 2020 Dr. rer. nat. at Ludwig-Maximilians-University Munich (AG Bramkamp), Thesis title: Dynamics of the Min system in Bacillus subtilis - An analysis using fluorescence and single- molecule localization microscopy
2012 - 2014 Master of Science at Ludwig-Maximilians-University Munich, Biology
2011 - 2012 Bachelor of Science (Honours) at the University of Aberdeen, Biomedical Sciences (Genetics /Immunology)
2009 - 2012 Bachelor of Science at the University Bonn-Rhein-Sieg,
Applied Biology
Publications
Hołówka J, Łebkowski T, Feddersen H, Giacomelli G, Drużka K, Makowski Ł, Trojanowski D, Broda N, Bramkamp M, Zakrzewska-Czerwińska J. 2023. Mycobacterial IHF is a highly dynamic nucleoid-associated protein that assists HupB in organizing chromatin. Frontiers in Microbiology 14.
https://doi.org/10.3389/fmicb.2023.1146406
Giacomelli G, Feddersen H, Bramkamp M. Overcoming the signal overlap in super-resolution microscopy - A beginner's guide to single-molecule localization microscopy colocalization. Wiley Analytical Science. 2022 Nov 9.
https://analyticalscience.wiley.com/do/10.1002/was.0004000306/
Giacomelli G*, Feddersen H*, Peng F, Martins GB, Grafemeyer M, Meyer F, Mayer B, Graumann PL, Bramkamp M. Subcellular Dynamics of a Conserved Bacterial Polar Scaffold Protein. Genes (Basel). 2022 Jan 30;13(2):278. https://doi.org/10.3390/genes13020278
Osorio-Valeriano M, Altegoer F, Das CK, Steinchen W, Panis G, Connolley L, Giacomelli G, Feddersen H, Corrales-Guerrero L, Giammarinaro PI, Hanßmann J, Bramkamp M, Viollier PH, Murray S, Schäfer LV, Bange G, Thanbichler M. The CTPase activity of ParB determines the size and dynamics of prokaryotic DNA partition complexes. Mol Cell. 2021 Oct 7;81(19):3992-4007.e10. https://doi.org/10.1016/j.molcel.2021.09.004
Kołodziej M, Trojanowski D, Bury K, Hołówka J, Paściak M, Matysik W, Kąkolewska H, Feddersen H, Giacomelli G, Bramkamp M, Konieczny I, Zakrzewska-Czerwińska J. Lsr2, a nucleoid-associated protein influencing mycobacterial cell cycle. Sci Rep 11, 2910 (2021).
https://doi.org/10.1038/s41598-021-82295-0
Feddersen H, Würthner L, Frey E, Bramkamp M. Dynamics of the Bacillus subtilis Min system. bioRxiv 020.04.29.068676 (2020).
https://doi.org/10.1101/2020.04.29.068676.
Feddersen H, Shin JY & Bramkamp M. Einzelmolekül-Lokalisationsmikroskopie mit mikrobiellen Proben. Biospektrum 25, 170–173 (2019). https://doi.org/10.1007/s12268-019-1027-9.
Stockmar I*, Feddersen H*, Cramer K, Gruber S, Jung K, Bramkamp M. Optimization of sample preparation and green color imaging using the mNeonGreen fluorescent protein in bacterial cells for photoactivated localization microscopy. Sci Rep 8, 10137 (2018).
https://doi.org/10.1038/s41598-018-28472-0.
